Malignant pleural effusion treated by tetracycline sclerotherapy. A comparison of single vs repeated instillation.
نویسندگان
چکیده
Fifty patients with malignant pleural effusion were randomized to receive one or two doses of tetracycline sclerotherapy. We found that a single sclerotherapy treatment with tetracycline at a dose of 20 mg/kg was as effective as two sclerotherapy treatments and provided symptomatic relief in 46 of the 50 patients.
منابع مشابه
Efficacy of short term versus long term tube thoracostomy drainage before tetracycline pleurodesis in the treatment of malignant pleural effusions.
BACKGROUND A study was undertaken to compare the efficacy of short term tube thoracostomy drainage with standard tube thoracostomy drainage before instillation of tetracycline for sclerotherapy of malignant pleural effusions. METHODS The study consisted of a randomised clinical trial in a sequential sample of 25 patients with malignant pleural effusions documented cytopathologically. Fifteen ...
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8 Boutin C, Rey F, Viallat JR. Etude randomiséede l'efficacitédu talcage thoracoscopique et de l'instillation de tetracycline dans le traitement des pleurésies cancereuses récidivantes. Rev Mal Respir 1985; 2:374 9 Sherman S. Ravikrishnan KP, Patel AS, Seidman JC. Optimum anesthesia with intrapleural lidocaine during chemical pleuro desis with tetracycline. Chest 1988; 93:533-36 10 Frank W,...
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Therapeutic tetracycline pleurodesis was performed on 14 different inoperable surgical patients having symptomatic recurrent pneumothoraces ( > 40 percent) and malignant pleural effusions over a period of six months in the medical/surgical units of Central Government Poly Clinic, Islamabad. The study included 9 males and 5 females ranging 27 59 years of their ages. Only one patient needed repea...
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Background: Patients with symptomatic malignant pleural effusion (MPE) may gain profit from pleurodesis for relief of dyspnea and in preventing the accumulation of fluid or air in the pleural space. Pleurodesis methods are palliative and regard the patient's symptoms and underlying disease condition that are different. The purpose of this study was to assess the efficacy of bleomycin in the tre...
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Malignant pleural effusions are associated with significant morbidity. Prompt clinical evaluation followed by aggressive treatment often results in successful palliation. This report summarizes the traditional and experimental approaches used in the management of malignant pleural effusion and provides an attempt at analysis of cost comparison and resource utilization associated with the use of...
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ورودعنوان ژورنال:
- Chest
دوره 93 6 شماره
صفحات -
تاریخ انتشار 1988